2222566-55-2

2222566-55-2 structure

2222566-55-2 structure

Name: T-Boc-n-amido-peg15-amine
Chemical Name: Boc-NH-PEG15-NH2
CAS Number: 2222566-55-2
Molecular Formula: C₃₇H₇₆N₂O₁₇
Molecular Weight: 821.00
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 12:15:48
Modify Date: 2024-01-08 20:47:39
Boc-NH-PEG15-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Boc-NH-PEG15-NH2
Synonyms	MFCD28385469

Description	Boc-NH-PEG15-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₃₇H₇₆N₂O₁₇
Molecular Weight	821.00