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2225903-66-0

2225903-66-0 structure

2225903-66-0 structure

Name: Bis-PEG13-acid
Chemical Name: Bis-PEG13-acid
CAS Number: 2225903-66-0
Molecular Formula: C₃₀H₅₈O₁₇
Molecular Weight: 690.77
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 18:00:16
Modify Date: 2024-01-23 07:26:36
Bis-PEG13-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Bis-PEG13-acid

Description	Bis-PEG13-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₃₀H₅₈O₁₇
Molecular Weight	690.77