887628-40-2

887628-40-2 structure
887628-40-2 structure
  • Name: SLc-nhs-(+)-biotin
  • Chemical Name: Biotin-C10-NHS Ester
  • CAS Number: 887628-40-2
  • Molecular Formula: C25H40N4O6S
  • Molecular Weight: 524.67
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 14:12:42
  • Modify Date: 2024-01-07 10:45:35
  • Biotin-C10-NHS Ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Biotin-C10-NHS Ester
Synonyms MFCD05865045
Description Biotin-C10-NHS Ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C25H40N4O6S
Molecular Weight 524.67