1428661-67-9

1428661-67-9 structure

1428661-67-9 structure

Name: Amino-Tri-(m-PEG4-ethoxymethyl)-methane
Chemical Name: Amino-Tri-(m-PEG4-ethoxymethyl)-methane
CAS Number: 1428661-67-9
Molecular Formula: C₄₀H₈₀N₄O₁₈
Molecular Weight: 905.08
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 17:33:12
Modify Date: 2024-01-23 12:46:50
Amino-Tri-(m-PEG4-ethoxymethyl)-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Amino-Tri-(m-PEG4-ethoxymethyl)-methane

Description	Amino-Tri-(m-PEG4-ethoxymethyl)-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₄₀H₈₀N₄O₁₈
Molecular Weight	905.08