2353410-13-4

2353410-13-4 structure

2353410-13-4 structure

Name: Ald-CH2-PEG8-azide
Chemical Name: Ald-CH2-PEG8-azide
CAS Number: 2353410-13-4
Molecular Formula: C₁₈H₃₅N₃O₉
Molecular Weight: 437.49
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 19:08:39
Modify Date: 2024-01-27 18:57:54
Ald-CH2-PEG8-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Ald-CH2-PEG8-azide

Description	Ald-CH2-PEG8-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₈H₃₅N₃O₉
Molecular Weight	437.49