361154-30-5

361154-30-5 structure

Name: Ac4ManNAz
Chemical Name: Ac4ManNAz
CAS Number: 361154-30-5
Molecular Formula: C₁₆H₂₂N₄O₁₀
Molecular Weight: 430.37
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-05 06:35:36
Modify Date: 2024-01-03 11:48:05
Ac4ManNAz is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Ac4ManNAz

Description	Ac4ManNAz is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.