1198151-75-5

1198151-75-5 structure

Name: Vapendavir diphosphate
Chemical Name: Vapendavir diphosphate
CAS Number: 1198151-75-5
Molecular Formula: C₂₁H₃₂N₄O₁₁P₂
Molecular Weight: 578.45
Catalog: Research Areas Infection
Create Date: 2020-04-12 19:35:45
Modify Date: 2024-01-09 20:04:23
Vapendavir diphosphate (BTA798 diphosphate) is a potent enteroviral capsid binder (CB). Vapendavir diphosphate (BTA798 diphosphate) possesses potent antiviral activity for enterovirus 71 (EV71) replication, with EC50 values of 0.5-1.4 μM in different EV71 strains[1][2].

Name	Vapendavir diphosphate

Description	Vapendavir diphosphate (BTA798 diphosphate) is a potent enteroviral capsid binder (CB). Vapendavir diphosphate (BTA798 diphosphate) possesses potent antiviral activity for enterovirus 71 (EV71) replication, with EC50 values of 0.5-1.4 μM in different EV71 strains[1][2].
Related Catalog	Research Areas >> Infection Research Areas >> Inflammation/Immunology
Target	EC50: 0.5-1.4 μM (EV71 strains)[1][2].
In Vitro	Vapendavir (BTA798) efficiently inhibit the in vitro replication of 21 EV71 strains/isolates that are representative of the different genogroups A, B, and C[2].
References	[1]. Tijsma A, et al. The capsid binder Vapendavir and the novel protease inhibitor SG85 inhibit enterovirus 71 replication. Antimicrob Agents Chemother. 2014 Nov;58(11):6990-2. [2]. Sun L, et al. Antiviral Activity of Broad-Spectrum and Enterovirus-Specific Inhibitors against Clinical Isolates of Enterovirus D68. Antimicrob Agents Chemother. 2015 Dec;59(12):7782-5.

Molecular Formula	C₂₁H₃₂N₄O₁₁P₂
Molecular Weight	578.45