2353409-92-2

2353409-92-2 structure

2353409-92-2 structure

Name: TCO-PEG8-amine
Chemical Name: TCO-PEG8-amine
CAS Number: 2353409-92-2
Molecular Formula: C₂₇H₅₂N₂O₁₀
Molecular Weight: 564.71
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-04-13 00:06:37
Modify Date: 2024-01-09 00:38:56
TCO-PEG8-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name	TCO-PEG8-amine

Description	TCO-PEG8-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References	[1]. Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238.

Molecular Formula	C₂₇H₅₂N₂O₁₀
Molecular Weight	564.71