888958-25-6
888958-25-6 structure
- Name: SARS-CoV-IN-1
- Chemical Name: SARS-CoV-IN-1
- CAS Number: 888958-25-6
- Molecular Formula: C23H16ClFeN3O
- Molecular Weight: 441.69
- Catalog: Signaling Pathways Anti-infection SARS-CoV
- Create Date: 2020-04-10 09:04:26
- Modify Date: 2025-08-27 10:28:05
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SARS-CoV-IN-1 is an effective inhibitor of SARS-CoV replication. SARS-CoV-IN-1 shows anti-Coronavirus activity with an EC50 of 4.9 μM in Vero cells. SARS-CoV-IN-1 inhibits the 3D7 and W2 strains of P. falciparum with IC50s of 15.4 and 133.2 nM; and IC90s of 25.7 and 459.1 nM; respectively. Antimalarial and antiviral activities[1].
| Name | SARS-CoV-IN-1 |
|---|
| Description | SARS-CoV-IN-1 is an effective inhibitor of SARS-CoV replication. SARS-CoV-IN-1 shows anti-Coronavirus activity with an EC50 of 4.9 μM in Vero cells. SARS-CoV-IN-1 inhibits the 3D7 and W2 strains of P. falciparum with IC50s of 15.4 and 133.2 nM; and IC90s of 25.7 and 459.1 nM; respectively. Antimalarial and antiviral activities[1]. |
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| Related Catalog | |
| Target |
EC50: 4.9 μM (SARS-CoV, in Vero cells)[1] IC50: 15.4 nM (3D7 P. falciparum), 133.2 nM (W2 P. falciparum)[1] IC90: 25.7 nM (3D7 P. falciparum), 459.1 nM (W2 P. falciparum)[1] |
| In Vitro | SARS-CoV-IN-1 (Compound 2) inhibits in vitro growth of Plasmodium falciparum far better than Chloroquine (CQ) [1]. |
| References |
| Molecular Formula | C23H16ClFeN3O |
|---|---|
| Molecular Weight | 441.69 |