2243566-42-7

2243566-42-7 structure

2243566-42-7 structure

Name: m-PEG5-triethoxysilane
Chemical Name: m-PEG5-triethoxysilane
CAS Number: 2243566-42-7
Molecular Formula: C₂₁H₄₅NO₉Si
Molecular Weight: 483.67
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-04-12 16:51:43
Modify Date: 2024-01-13 17:33:07
m-PEG5-triethoxysilane is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name	m-PEG5-triethoxysilane

Description	m-PEG5-triethoxysilane is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₂₁H₄₅NO₉Si
Molecular Weight	483.67