2353409-59-1

2353409-59-1 structure

2353409-59-1 structure

Name: Biotin-PEG7-thiourea
Chemical Name: Biotin-PEG7-thiourea
CAS Number: 2353409-59-1
Molecular Formula: C₂₇H₅₁N₅O₉S₂
Molecular Weight: 653.85
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-04-13 10:41:39
Modify Date: 2024-01-13 23:45:05
Biotin-PEG7-thiourea is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Biotin-PEG7-thiourea

Description	Biotin-PEG7-thiourea is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.

Molecular Formula	C₂₇H₅₁N₅O₉S₂
Molecular Weight	653.85