863239-60-5
863239-60-5 structure
- Name: Glyco-Obeticholic acid
- Chemical Name: Glyco-Obeticholic acid
- CAS Number: 863239-60-5
- Molecular Formula: C28H47NO5
- Molecular Weight: 477.68
- Catalog: Signaling Pathways Metabolic Enzyme/Protease FXR
- Create Date: 2020-01-23 19:11:51
- Modify Date: 2025-09-16 13:21:03
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Glyco-obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is a farnesoid X receptor (FXR) agonist[1].
| Name | Glyco-Obeticholic acid |
|---|
| Description | Glyco-obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is a farnesoid X receptor (FXR) agonist[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Obeticholic acid is conjugated with glycine in the liver to form glycol-obeticholic acid, which is secreted into bile. Microorganisms in the ileum and colon can deconjugate glyco-obeticholic acid, converting it into the parent drug, which may then be reabsorbed or excreted in faeces[1]. |
| References |
[1]. Markham A, et al. Obeticholic Acid: First Global Approval. Drugs. 2016 Aug;76(12):1221-6. |
| Molecular Formula | C28H47NO5 |
|---|---|
| Molecular Weight | 477.68 |