850330-77-7
850330-77-7 structure
- Name: LMD-A
- Chemical Name: LMD-A
- CAS Number: 850330-77-7
- Molecular Formula: C27H32N4O4S
- Molecular Weight: 508.637
- Create Date: 2020-01-11 16:41:49
- Modify Date: 2024-01-18 20:05:09
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LMD-A (CCR8 antagonist LMD-A) is a highly potent, small molecule antagonist of chemokine receptor CCR8 with EC50 of 2.5 nM; inhibits 10 nM CCL1-induced activation of CCR8 with EC50 of 12 nM, inhibits 4DE4 cells cell migration induced by 3 nM CCL1 with EC50 of 0.58 nM.
| Name | LMD-A |
|---|
| Description | LMD-A (CCR8 antagonist LMD-A) is a highly potent, small molecule antagonist of chemokine receptor CCR8 with EC50 of 2.5 nM; inhibits 10 nM CCL1-induced activation of CCR8 with EC50 of 12 nM, inhibits 4DE4 cells cell migration induced by 3 nM CCL1 with EC50 of 0.58 nM. |
|---|---|
| References | References 1. Rummel PC, et al. Br J Pharmacol. 2012 Nov;167(6):1206-17. 2. Barington L, et al. J Biol Chem. 2016 Jul 29;291(31):16208-20. View Related Products by Target Chemokine Receptor (CCR and CXCR) |
| Molecular Formula | C27H32N4O4S |
|---|---|
| Molecular Weight | 508.637 |