776300-37-9
776300-37-9 structure
- Name: AUDA-BE
- Chemical Name: AUDA-BE
- CAS Number: 776300-37-9
- Molecular Formula: C27H48N2O3
- Molecular Weight: 448.692
- Create Date: 2020-01-12 10:26:49
- Modify Date: 2025-09-18 10:27:41
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The prodrug of AUDA, a potent inhibitor of sEH (soluble epoxide hydrolase) with IC50 of 50 nM and 100 nM for mouse sEH and human sEH, respectively; prevents LPS-induced mortality and preserved systolic blood pressure, reduces NO production in mice.
| Name | AUDA-BE |
|---|
| Description | The prodrug of AUDA, a potent inhibitor of sEH (soluble epoxide hydrolase) with IC50 of 50 nM and 100 nM for mouse sEH and human sEH, respectively; prevents LPS-induced mortality and preserved systolic blood pressure, reduces NO production in mice. |
|---|---|
| References | References 1. Morisseau C, et al. Biochem Pharmacol. 2002 May 1;63(9):1599-608. 2. Schmelzer KR, et al. Proc Natl Acad Sci U S A. 2005 Jul 12;102(28):9772-7. 3. Motoki A, et al. Am J Physiol Heart Circ Physiol. 2008 Nov;295(5):H2128-34. View Related Products by Target Other Targets |
| Molecular Formula | C27H48N2O3 |
|---|---|
| Molecular Weight | 448.692 |