2056238-04-9
2056238-04-9 structure
- Name: Mcl1-IN-26
- Chemical Name: Mcl1-IN-26
- CAS Number: 2056238-04-9
- Molecular Formula: C45H52ClN5O6S
- Molecular Weight: 826.45
- Catalog: Signaling Pathways Apoptosis Bcl-2 Family
- Create Date: 2020-01-20 13:36:56
- Modify Date: 2024-04-08 18:28:03
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A novel potent, selective Mcl-1 inhibitor with IC50 of <3 nM in FRET assays; displays >1,000-fold selectivity over Bcl-2 and Bcl-xL; induces cleaved caspase-3 in MV4-11 cells with IC50 of 3.78 uM.
| Name | Mcl1-IN-26 |
|---|
| Description | A novel potent, selective Mcl-1 inhibitor with IC50 of <3 nM in FRET assays; displays >1,000-fold selectivity over Bcl-2 and Bcl-xL; induces cleaved caspase-3 in MV4-11 cells with IC50 of 3.78 uM. |
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| References | References 1. Johannes JW, et al. ACS Med Chem Lett. 2016 Dec 27;8(2):239-244. View Related Products by Target Bcl-2 |
| Molecular Formula | C45H52ClN5O6S |
|---|---|
| Molecular Weight | 826.45 |