205592-79-6
205592-79-6 structure
- Name: 5-NITP
- Chemical Name: 5-NITP
- CAS Number: 205592-79-6
- Molecular Formula: C13H17N2O14P3
- Molecular Weight: 518.2
- Create Date: 2020-01-19 23:18:55
- Modify Date: 2025-12-29 18:37:12
-
5-NITP (5-nitro-indolyl-2'-deoxyribose triphosphate) is a non-natural nucleotide that inhibits ribonucleotide reductase (hRR) with IC50 of 170 uM, demonstrates anti-cancer effects against leukemia cells by altering cell-cycle progression.
| Name | 5-NITP |
|---|
| Description | 5-NITP (5-nitro-indolyl-2'-deoxyribose triphosphate) is a non-natural nucleotide that inhibits ribonucleotide reductase (hRR) with IC50 of 170 uM, demonstrates anti-cancer effects against leukemia cells by altering cell-cycle progression. |
|---|---|
| References | References 1. Ahmad MF, et al. Mol Cancer Ther. 2012 Oct;11(10):2077-86. 2. Choi JS, et al. Cancer Res. 2018 Feb 15;78(4):1083-1096. View Related Products by Target Nucleoside Antimetabolite/Analog |
| Molecular Formula | C13H17N2O14P3 |
|---|---|
| Molecular Weight | 518.2 |