1998149-15-7
1998149-15-7 structure
- Name: Disarib
- Chemical Name: Disarib
- CAS Number: 1998149-15-7
- Molecular Formula: C26H16BrClN4OS
- Molecular Weight: 547.855
- Create Date: 2020-01-20 00:20:56
- Modify Date: 2025-08-25 15:41:41
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Disarib is a novel BCL2-specific inhibitor that binds predominantly to the BH1 domain, demonstrates strong affinity to BCL2, but not to other antiapoptotic BCL2 family members(BCL-xL, BCL2A1 etc.); is a novel BCL2 inhibitor with a unique mechanism of BCL2 inhibition.
| Name | Disarib |
|---|
| Description | Disarib is a novel BCL2-specific inhibitor that binds predominantly to the BH1 domain, demonstrates strong affinity to BCL2, but not to other antiapoptotic BCL2 family members(BCL-xL, BCL2A1 etc.); is a novel BCL2 inhibitor with a unique mechanism of BCL2 inhibition. |
|---|---|
| References | References 1. Iyer D, et al. FEBS J. 2016 Sep;283(18):3408-37. 2. Vartak SV, et al. Biochem Pharmacol. 2016 Dec 15;122:10-22. 3. Vartak SV, et al. Biochem Pharmacol. 2017 May 1;131:16-28. doi: View Related Products by Target Bcl-2 |
| Molecular Formula | C26H16BrClN4OS |
|---|---|
| Molecular Weight | 547.855 |