Top Suppliers:I want be here


790241-43-9

790241-43-9 structure
790241-43-9 structure
  • Name: DB818
  • Chemical Name: DB818
  • CAS Number: 790241-43-9
  • Molecular Formula: C19H16N6S
  • Molecular Weight: 360.439
  • Catalog: Signaling Pathways Apoptosis Apoptosis
  • Create Date: 2020-01-11 16:18:50
  • Modify Date: 2024-09-08 16:11:42
  • DB818 (DB-818, DB 818) is a small molecule inhibitor of HOXA9/DNA interaction through binding as minor groove DNA ligand on the HOXA9 cognate sequence; directly bind to HOXA9-cognate sequence with Kd value of 4.6 nM (HBS sequence); alters HOXA9-mediated transcription, cell survival and cell cycle inHOXA9-mediated HOXA9-expressing murine MigA9 cell line.

Name DB818
Description DB818 (DB-818, DB 818) is a small molecule inhibitor of HOXA9/DNA interaction through binding as minor groove DNA ligand on the HOXA9 cognate sequence; directly bind to HOXA9-cognate sequence with Kd value of 4.6 nM (HBS sequence); alters HOXA9-mediated transcription, cell survival and cell cycle inHOXA9-mediated HOXA9-expressing murine MigA9 cell line.
References References 1. Depauw S, et al. J Med Chem. 2019 Jan 15. doi: 10.1021/acs.jmedchem.8b01448. View Related Products by Target Other Targets
Molecular Formula C19H16N6S
Molecular Weight 360.439