902955-25-3
902955-25-3 structure
- Name: CeMMEC2
- Chemical Name: N-[2-(1-Cyclohexen-1-yl)ethyl]-3-methyl[1,2,4]triazolo[4,3-b]pyridazin-6-amine
- CAS Number: 902955-25-3
- Molecular Formula: C14H19N5
- Molecular Weight: 257.334
- Catalog: Signaling Pathways Epigenetics Epigenetic Reader Domain
- Create Date: 2020-01-11 18:41:50
- Modify Date: 2024-01-26 09:56:56
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CeMMEC2 is a novel potent BRD4 inhibitor with IC50 of 0.9 uM, binds to both bromodomains of BRD4, comparably to (S)-JQ1.
| Name | N-[2-(1-Cyclohexen-1-yl)ethyl]-3-methyl[1,2,4]triazolo[4,3-b]pyridazin-6-amine |
|---|---|
| Synonyms |
1,2,4-Triazolo[4,3-b]pyridazin-6-amine, N-[2-(1-cyclohexen-1-yl)ethyl]-3-methyl-
N-[2-(1-Cyclohexen-1-yl)ethyl]-3-methyl[1,2,4]triazolo[4,3-b]pyridazin-6-amine |
| Description | CeMMEC2 is a novel potent BRD4 inhibitor with IC50 of 0.9 uM, binds to both bromodomains of BRD4, comparably to (S)-JQ1. |
|---|---|
| References | References 1. Sdelci S, et al. Nat Chem Biol. 2016 Jul;12(7):504-10. 2. Blank, J. et al. WPO patent WO/2014/191894 (2014). View Related Products by Target Bromodomain |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Molecular Formula | C14H19N5 |
| Molecular Weight | 257.334 |
| Exact Mass | 257.164032 |
| LogP | 2.41 |
| Index of Refraction | 1.673 |