1646795-59-6
1646795-59-6 structure
- Name: KC01
- Chemical Name: (Z)-6-(2-Oxo-4-tridecyloxetan-3-ylidene)hexanamide
- CAS Number: 1646795-59-6
- Molecular Formula: C22H39NO3
- Molecular Weight: 365.550
- Catalog: Research Areas Inflammation/Immunology
- Create Date: 2020-01-11 22:26:33
- Modify Date: 2024-09-15 22:13:48
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KC01 is a potent and selective inhibitor of ABHD16A with IC50 of 90 nM for hABHD16A, 520 nM for mABHD16A; shows significant reductions in all detected cellular lyso-PSs, no activity in other lipids, including PSs, PCs, PEs, lyso-PCs, lyso-PEs, or monoacylglycerols (MAGs); decreases both lyso-PSs and lipopolysaccharide-induced cytokine production in mouse macrophages.
| Name | (Z)-6-(2-Oxo-4-tridecyloxetan-3-ylidene)hexanamide |
|---|---|
| Synonyms |
Hexanamide, 6-(2-oxo-4-tridecyl-3-oxetanylidene)-, (6Z)-
(6Z)-6-(2-Oxo-4-tridecyl-3-oxetanylidene)hexanamide (Z)-6-(2-Oxo-4-tridecyloxetan-3-ylidene)hexanamide |
| Description | KC01 is a potent and selective inhibitor of ABHD16A with IC50 of 90 nM for hABHD16A, 520 nM for mABHD16A; shows significant reductions in all detected cellular lyso-PSs, no activity in other lipids, including PSs, PCs, PEs, lyso-PCs, lyso-PEs, or monoacylglycerols (MAGs); decreases both lyso-PSs and lipopolysaccharide-induced cytokine production in mouse macrophages. |
|---|---|
| References | References 1. Kamat SS, et al. Nat Chem Biol. 2015 Feb;11(2):164-71. View Related Products by Target Other Targets |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 568.7±33.0 °C at 760 mmHg |
| Molecular Formula | C22H39NO3 |
| Molecular Weight | 365.550 |
| Flash Point | 190.5±21.7 °C |
| Exact Mass | 365.292999 |
| LogP | 5.72 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.514 |