851305-26-5

851305-26-5 structure

Name: LJ 001
Chemical Name: LJ-001
CAS Number: 851305-26-5
Molecular Formula: C₁₇H₁₃NO₂S₂
Molecular Weight: 327.421
Catalog: Signaling Pathways Anti-infection HCV
Create Date: 2020-01-11 19:16:07
Modify Date: 2024-01-06 19:41:17
LJ 001 ((LJ-001, LJ001) is a broad-spectrum antiviral agent targeting entry of enveloped viruses, including influenza A, filoviruses, poxviruses, arenaviruses, bunyaviruses, paramyxoviruses, flaviviruses, and HIV-1; specifically intercalates into viral membranes, irreversibly inactivates virions while leaving functionally intact envelope proteins, and inhibits viral entry at a step after virus binding but before virus-cell fusion; specifically inhibits virus-cell but not cell-cell fusion

Name	LJ-001
Synonyms	(5Z)-3-Allyl-5-[(5-phenyl-2-furyl)methylene]-2-thioxo-1,3-thiazolidin-4-one (5Z)-5-[(5-phenylfuran-2-yl)methylidene]-3-(prop-2-en-1-yl)-2-thioxo-1,3-thiazolidin-4-one 8646IPJ1AP 4-Thiazolidinone, 5-[(5-phenyl-2-furanyl)methylene]-3-(2-propen-1-yl)-2-thioxo-, (5Z)- LJ-001

Description	LJ 001 ((LJ-001, LJ001) is a broad-spectrum antiviral agent targeting entry of enveloped viruses, including influenza A, filoviruses, poxviruses, arenaviruses, bunyaviruses, paramyxoviruses, flaviviruses, and HIV-1; specifically intercalates into viral membranes, irreversibly inactivates virions while leaving functionally intact envelope proteins, and inhibits viral entry at a step after virus binding but before virus-cell fusion; specifically inhibits virus-cell but not cell-cell fusion
References	References 1. Wolf MC, et al. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3157-62. 2. Vigant F, et al. PLoS Pathog. 2013;9(4):e1003297. 3. Balmer BF, et al. J Virol. 2017 Jan 31;91(4). pii: e02181-16. View Related Products by Target Influenza Virus