1415251-36-3
1415251-36-3 structure
- Name: WJ460
- Chemical Name: WJ460
- CAS Number: 1415251-36-3
- Molecular Formula: C27H28N2O3S
- Molecular Weight: 460.59
- Catalog: Research Areas Cancer
- Create Date: 2019-10-09 18:23:29
- Modify Date: 2025-08-25 16:45:54
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WJ460 is a potent myoferlin (MYOF) inhibitor, which interacts directly with MYOF and exerts anti-metastatic activity in the nanomolar range in breast cancer cells[1].
| Name | WJ460 |
|---|
| Description | WJ460 is a potent myoferlin (MYOF) inhibitor, which interacts directly with MYOF and exerts anti-metastatic activity in the nanomolar range in breast cancer cells[1]. |
|---|---|
| Related Catalog | |
| Target |
MYOF[1] |
| In Vitro | WJ460 blocks breast cancer cell invasion with IC50 values of 43.37 ± 3.42 nM in MDA-MB-231 and 36.40 ± 4.51 nM in BT549 cells. WJ460 treatment remarkably inhibits MDA-MB-231 and BT549 cell invasion through Collagen I in a dose-dependent manner[1]. |
| In Vivo | WJ460 inhibits breast tumor growth, angiogenesis, and spontaneous metastasis in a spontaneous metastasis model[1]. |
| References |
| Molecular Formula | C27H28N2O3S |
|---|---|
| Molecular Weight | 460.59 |