170111-28-1

170111-28-1 structure

170111-28-1 structure

Name: LHVS
Chemical Name: LHVS
CAS Number: 170111-28-1
Molecular Formula: C₂₈H₃₇N₃O₅S
Molecular Weight: 527.68
Catalog: Signaling Pathways Anti-infection Parasite
Create Date: 2019-10-09 09:10:29
Modify Date: 2024-01-12 08:44:06
LHVS is a potent, non-selective cysteine protease inhibitor[1]. LHVS effectively blocks T. gondii microneme protein secretion (IC50=10 μM), gliding motility, and cell invasion[2].

Name	LHVS

Description	LHVS is a potent, non-selective cysteine protease inhibitor[1]. LHVS effectively blocks T. gondii microneme protein secretion (IC50=10 μM), gliding motility, and cell invasion[2].
Related Catalog	Signaling Pathways >> Anti-infection >> Parasite Research Areas >> Infection Signaling Pathways >> Metabolic Enzyme/Protease >> Cathepsin
Target	Cysteine protease[1]
References	[1]. Wilson SR, et al. Cathepsin K activity-dependent regulation of osteoclast actin ring formation and bone resorption. J Biol Chem. 2009 Jan 23;284(4):2584-92. [2]. Teo CF, et al.Cysteine protease inhibitors block Toxoplasma gondii microneme secretion and cell invasion. Antimicrob Agents Chemother. 2007 Feb;51(2):679-88.

Molecular Formula	C₂₈H₃₇N₃O₅S
Molecular Weight	527.68