2351103-63-2

2351103-63-2 structure

Name: E3 ligase Ligand-Linker Conjugates 49
Chemical Name: E3 ligase Ligand-Linker Conjugates 49
CAS Number: 2351103-63-2
Molecular Formula: C₃₁H₄₄N₄O₁₁
Molecular Weight: 648.70
Catalog: Signaling Pathways PROTAC E3 Ligase Ligand-Linker Conjugate
Create Date: 2019-09-07 17:58:16
Modify Date: 2024-01-12 18:22:28
E3 ligase Ligand-Linker Conjugates 49 incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase, and a PROTAC linker. E3 ligase Ligand-Linker Conjugates 49 can be used to design PROTAC degrader.

Name	E3 ligase Ligand-Linker Conjugates 49

Description	E3 ligase Ligand-Linker Conjugates 49 incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase, and a PROTAC linker. E3 ligase Ligand-Linker Conjugates 49 can be used to design PROTAC degrader.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
Target	Cereblon
References	[1]. Zhou B, et al. Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins withPicomolar Cellular Potencies and Capable of Achieving Tumor Regression. J Med Chem. 2018 Jan 25;61(2):462-481.

Molecular Formula	C₃₁H₄₄N₄O₁₁
Molecular Weight	648.70