1629277-36-6

1629277-36-6 structure
1629277-36-6 structure
  • Name: PNZ5
  • Chemical Name: PNZ5
  • CAS Number: 1629277-36-6
  • Molecular Formula: C20H18N2O2
  • Molecular Weight: 318.37
  • Catalog: Signaling Pathways Epigenetics Epigenetic Reader Domain
  • Create Date: 2019-08-04 11:25:59
  • Modify Date: 2024-01-09 17:53:05
  • PNZ5 is a potent and isoxazole-based pan-BET inhibitor with high selectivity and potency similar to the well-established (+)-JQ1, with a KD of 5.43 nM for BRD4(1)[1].

Name PNZ5
Description PNZ5 is a potent and isoxazole-based pan-BET inhibitor with high selectivity and potency similar to the well-established (+)-JQ1, with a KD of 5.43 nM for BRD4(1)[1].
Related Catalog
Target

BRD4(1):5.43 nM (Kd)

References

[1]. Montenegro RC, et al. BET inhibition as a new strategy for the treatment of gastric cancer. Oncotarget. 2016 Jul 12;7(28):43997-44012.

Molecular Formula C20H18N2O2
Molecular Weight 318.37
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