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1384860-29-0

1384860-29-0 structure
1384860-29-0 structure
  • Name: Conteltinib
  • Chemical Name: Conteltinib
  • CAS Number: 1384860-29-0
  • Molecular Formula: C32H45N9O3S
  • Molecular Weight: 635.82
  • Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK FAK
  • Create Date: 2019-08-04 11:52:58
  • Modify Date: 2024-01-03 16:00:47
  • Conteltinib (CT-707) is a multi-kinase inhibitor targeting FAK, ALK, and Pyk2. Conteltinib (CT-707) exerts significant inhibitory effect on FAK with an IC50 of 1.6 nM[1].

Name Conteltinib
Description Conteltinib (CT-707) is a multi-kinase inhibitor targeting FAK, ALK, and Pyk2. Conteltinib (CT-707) exerts significant inhibitory effect on FAK with an IC50 of 1.6 nM[1].
Related Catalog
Target

IC50: 1.6 nM (FAK)[1]

References

[1]. Wang DD, et al. CT-707, a Novel FAK Inhibitor, Synergizes with Cabozantinib to Suppress Hepatocellular Carcinoma by Blocking Cabozantinib-Induced FAK Activation. Mol Cancer Ther. 2016 Dec;15(12):2916-2925.

Molecular Formula C32H45N9O3S
Molecular Weight 635.82