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2068119-11-7

2068119-11-7 structure
2068119-11-7 structure
  • Name: S18-000003
  • Chemical Name: S18-000003
  • CAS Number: 2068119-11-7
  • Molecular Formula: C26H25F3N2O4S
  • Molecular Weight: 518.55
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease ROR
  • Create Date: 2019-06-30 18:54:23
  • Modify Date: 2025-09-13 23:39:02
  • S18-000003 is a potent orally bioavailable retinoic acid receptor-related orphan receptor-gamma-t (RORγt) inhibitor with an IC50 of 29 nM. S18-000003 inhibits IL-17 production[1].

Name S18-000003
Description S18-000003 is a potent orally bioavailable retinoic acid receptor-related orphan receptor-gamma-t (RORγt) inhibitor with an IC50 of 29 nM. S18-000003 inhibits IL-17 production[1].
Related Catalog
Target

IC50: 29 nM (RORγt)[1]

References

[1]. Sasaki Y, et al. Discovery of a potent orally bioavailable retinoic acid receptor-related orphan receptor-gamma-t (RORγt) inhibitor, S18-000003. Bioorg Med Chem Lett. 2018 Dec 1;28(22):3549-3553.

Molecular Formula C26H25F3N2O4S
Molecular Weight 518.55
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