Shanghai Nianxing Industrial Co., Ltd
China
Product Name: GW284543
Price: Check
Purity: 99.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: GW284543 (UNC10225170)
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

DC Chemicals Limited
China
Product Name: GW284543 (UNC10225170)
Price: $500.0/100mg $850.0/250mg $1700.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

790186-68-4

790186-68-4 structure

790186-68-4 structure

Name: GW284543
Chemical Name: GW284543
CAS Number: 790186-68-4
Molecular Formula: C₂₃H₂₀N₂O₃
Molecular Weight: 372.42
Catalog: Signaling Pathways MAPK/ERK Pathway MEK
Create Date: 2019-06-29 11:24:05
Modify Date: 2025-08-27 11:25:26
GW284543 (UNC10225170) is a selective MEK5 inhibitor[1].

Name	GW284543

Description	GW284543 (UNC10225170) is a selective MEK5 inhibitor[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> MAPK/ERK Pathway >> MEK
Target	MEK5
In Vitro	GW284543 (UNC10225170) treatment dose dependently inhibits MEK5, as determined by reductions in pERK5, and decreased endogenous MYC protein[1].
References	[1]. Vaseva AV, et al. KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism. Cancer Cell. 2018 Nov 12;34(5):807-822.e7.

Molecular Formula	C₂₃H₂₀N₂O₃
Molecular Weight	372.42
Storage condition	2-8℃

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