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790186-68-4

790186-68-4 structure
790186-68-4 structure
  • Name: GW284543
  • Chemical Name: GW284543
  • CAS Number: 790186-68-4
  • Molecular Formula: C23H20N2O3
  • Molecular Weight: 372.42
  • Catalog: Signaling Pathways MAPK/ERK Pathway MEK
  • Create Date: 2019-06-29 11:24:05
  • Modify Date: 2024-01-10 16:13:37
  • GW284543 (UNC10225170) is a selective MEK5 inhibitor[1].

Name GW284543
Description GW284543 (UNC10225170) is a selective MEK5 inhibitor[1].
Related Catalog
Target

MEK5

In Vitro GW284543 (UNC10225170) treatment dose dependently inhibits MEK5, as determined by reductions in pERK5, and decreased endogenous MYC protein[1].
References

[1]. Vaseva AV, et al. KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism. Cancer Cell. 2018 Nov 12;34(5):807-822.e7.

Molecular Formula C23H20N2O3
Molecular Weight 372.42
Storage condition 2-8℃