2247544-02-9
2247544-02-9 structure
- Name: WS-383 hydrochloride
- Chemical Name: WS-383
- CAS Number: 2247544-02-9
- Molecular Formula: C18H21Cl2N9S2
- Molecular Weight: 498.46
- Catalog: Research Areas Cancer
- Create Date: 2019-06-01 23:06:08
- Modify Date: 2025-08-25 19:11:36
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WS-383 is a potent, selective and reversible inhibitor of DCN1-UBC12 interaction, with an IC50 of 11 nM. WS-383 inhibits Cul3/1 neddylation, induces accumulation of p21, p27 and NRF2[1].
| Name | WS-383 |
|---|
| Description | WS-383 is a potent, selective and reversible inhibitor of DCN1-UBC12 interaction, with an IC50 of 11 nM. WS-383 inhibits Cul3/1 neddylation, induces accumulation of p21, p27 and NRF2[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 11 nM (DCN1-UBC12 interaction)[1] |
| References |
| Molecular Formula | C18H21Cl2N9S2 |
|---|---|
| Molecular Weight | 498.46 |