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2215852-91-6

2215852-91-6 structure
2215852-91-6 structure
  • Name: GSK3395879
  • Chemical Name: GSK3395879
  • CAS Number: 2215852-91-6
  • Molecular Formula: C20H15F4N3O5S
  • Molecular Weight: 485.41
  • Catalog: Signaling Pathways Membrane Transporter/Ion Channel TRP Channel
  • Create Date: 2019-06-04 18:10:27
  • Modify Date: 2024-01-19 12:06:30
  • GSK3395879 is a selective and orally bioavailable transient receptor potential vanilloid-4 (TRPV4) antagonist with an IC50 of 1 nM for hTRPV4[1].

Name GSK3395879
Description GSK3395879 is a selective and orally bioavailable transient receptor potential vanilloid-4 (TRPV4) antagonist with an IC50 of 1 nM for hTRPV4[1].
Related Catalog
Target

IC50: 1 nM (hTRPV4)[1]

References

[1]. Brnardic EJ, et al. Discovery of Pyrrolidine Sulfonamides as Selective and Orally Bioavailable Antagonists of Transient Receptor Potential Vanilloid-4 (TRPV4). J Med Chem. 2018 Nov 8;61(21):9738-9755.

Molecular Formula C20H15F4N3O5S
Molecular Weight 485.41