1450806-98-0
1450806-98-0 structure
- Name: GLP-1(7-37)acetate
- Chemical Name: GLP-1(7-37) acetate
- CAS Number: 1450806-98-0
- Molecular Formula: C153H232N40O49
- Molecular Weight: 3415.72
- Catalog: Signaling Pathways GPCR/G Protein Glucagon Receptor
- Create Date: 2019-06-02 13:10:56
- Modify Date: 2024-01-02 20:02:13
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GLP-1(7-37) acetate is an intestinal insulinotropic hormone that augments glucose induced insulin secretion[1].
| Name | GLP-1(7-37) acetate |
|---|
| Description | GLP-1(7-37) acetate is an intestinal insulinotropic hormone that augments glucose induced insulin secretion[1]. |
|---|---|
| Related Catalog | |
| In Vivo | GLP-1(7-37) (0.5, 5 or 50 pmol/min/kg) infused during the second hour of a 2-hour 11-mM hyperglycemic clamp produces a dose-related enhancement of the glucose-stimulated increase in plasma insulin concentration and an increased rate of glucose infusion in rats[2]. Infusion of GLP-1(7-37) (5 pmol/min/kg) from 1 hour through 7 hours produces a sustained increase in plasma insulin concentration relative to levels in rats infused with vehicle in rats with maintained glucose concentration at 11 mM[2]. Animal Model: Male Sprague-Dawley rats weighing 300 to 350 g with glucose IV at a variablerate for 7 hours to maintain plasma glucose concentration at 11 mM[2]. Dosage: 5 pmol/min/kg. Administration: IV from 1 hour through 7 hours[2]. Result: Produced a sustained increase in plasma insulin concentration relative to levels in rats infused with vehicle. Animal Model: Male Sprague-Dawley rats weighing 300 to 350 g with maintained plasma glucose concentration at 11 mM[2]. Dosage: 0.5, 5 or 50 pmol/min/kg. Administration: IV during the second hour of a 2-hour 11-mmol/L hyperglycemic clamp. Result: Produced a dose-related enhancement of the glucose-stimulated increase in plasma insulin concentration and an increased rate of glucose infusion. |
| References |
| Molecular Formula | C153H232N40O49 |
|---|---|
| Molecular Weight | 3415.72 |
| Storage condition | -20°C |