929300-19-6

929300-19-6 structure

Name: AZ084
Chemical Name: AZ084
CAS Number: 929300-19-6
Molecular Formula: C₂₆H₃₄N₄O₂
Molecular Weight: 434.57
Catalog: Signaling Pathways GPCR/G Protein CCR
Create Date: 2019-06-01 18:30:56
Modify Date: 2024-01-11 20:32:53
AZ084 is a potent, selective, allosteric and oral active CCR8 antagonist, with a Ki of 0.9 nM. Has potential to treat asthma[1].

Name	AZ084

Description	AZ084 is a potent, selective, allosteric and oral active CCR8 antagonist, with a Ki of 0.9 nM. Has potential to treat asthma[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> CCR Signaling Pathways >> Immunology/Inflammation >> CCR Research Areas >> Inflammation/Immunology
Target	CCR8:0.9 nM (Ki)
References	[1]. Connolly S, et al. Orally bioavailable allosteric CCR8 antagonists inhibit dendritic cell, T cell and eosinophil migration. Biochem Pharmacol. 2012 Mar 15;83(6):778-87.