1359993-59-1

1359993-59-1 structure

Name: Telratolimod
Chemical Name: Telratolimod
CAS Number: 1359993-59-1
Molecular Formula: C₃₆H₅₉N₅O₂
Molecular Weight: 593.89
Catalog: Signaling Pathways Immunology/Inflammation Toll-like Receptor (TLR)
Create Date: 2019-02-24 17:48:37
Modify Date: 2024-01-09 23:50:54
Telratolimod is a toll like receptors 7/8 (TLR7/8) agonist, with antitumor activity.

Name	Telratolimod

Description	Telratolimod is a toll like receptors 7/8 (TLR7/8) agonist, with antitumor activity.
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR) Research Areas >> Cancer
Target	TLR7/8[1]
In Vitro	Telratolimod (3M-052) is a toll like receptors 7/8 (TLR7/8) agonist, with antitumor activity[1].
In Vivo	Telratolimod (50 μg) inhibits the tumor volume, and more potently blocks tumor gowth in combination with CpG ODN in BALB/c mice bearing CT26 colon carcinoma cells. Telratolimod (100 μg) plus 200 μg of CpG ODN slows tumor growth and prolongs survival of mice bearing large tumors[1].
References	[1]. Zhao BG, et al. Combination therapy targeting toll like receptors 7, 8 and 9 eliminates large established tumors. J Immunother Cancer. 2014 May 13;2:12.