10538-99-5

10538-99-5 structure

Name: LY 345899
Chemical Name: LY 345899
CAS Number: 10538-99-5
Molecular Formula: C₂₀H₂₁N₇O₇
Molecular Weight: 471.42
Catalog: Research Areas Metabolic Disease
Create Date: 2019-02-17 17:47:21
Modify Date: 2025-08-25 12:13:03
LY 345899 is a human cytosolic methylenetetrahydrofolate dehydrogenase/cyclohydrolase (DC301) inhibitor, with a Ki of 0.018 μM.

Name	LY 345899

Description	LY 345899 is a human cytosolic methylenetetrahydrofolate dehydrogenase/cyclohydrolase (DC301) inhibitor, with a Ki of 0.018 μM.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
Target	Ki: 0.018 μM (DC301)[1].
References	[1]. Schmidt A, et al. Structures of three inhibitor complexes provide insight into the reaction mechanism of the human methylenetetrahydrofolate dehydrogenase/cyclohydrolase. Biochemistry. 2000 May 30;39(21):6325-35.