2138838-57-8

2138838-57-8 structure
2138838-57-8 structure
  • Name: HS80
  • Chemical Name: HS80
  • CAS Number: 2138838-57-8
  • Molecular Formula: C19H22N4S
  • Molecular Weight: 338.47
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease Fatty Acid Synthase (FAS)
  • Create Date: 2019-02-09 09:52:28
  • Modify Date: 2024-01-03 15:18:42
  • HS-80 is an enantiomer of Fasnall, which is a selective fatty acid synthase (FASN) inhibitor. HS-80 is able to inhibit the incorporation of tritiated acetate into lipids with an IC50 of 7.13 μM.

Name HS80
Description HS-80 is an enantiomer of Fasnall, which is a selective fatty acid synthase (FASN) inhibitor. HS-80 is able to inhibit the incorporation of tritiated acetate into lipids with an IC50 of 7.13 μM.
Related Catalog
Target

FASN[1]

In Vitro Fasnall, a thiophenopyrimidine selectively targeting FASN through its co-factor binding sites. Fasnall has anti-proliferative activity and induces apoptosis in breast cancer cells[1].
References

[1]. Alwarawrah Y, et al. Fasnall, a Selective FASN Inhibitor, Shows Potent Anti-tumor Activity in the MMTV-Neu Model of HER2(+) Breast Cancer. Cell Chem Biol. 2016 Jun 23;23(6):678-88.

Molecular Formula C19H22N4S
Molecular Weight 338.47