2095616-82-1
2095616-82-1 structure
- Name: CH7057288
- Chemical Name: CH7057288
- CAS Number: 2095616-82-1
- Molecular Formula: C32H31N3O5S
- Molecular Weight: 569.67
- Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK Trk Receptor
- Create Date: 2019-01-20 09:00:36
- Modify Date: 2024-01-08 21:51:27
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CH7057288 is a potent and selective TRK inhibitor.
| Name | CH7057288 |
|---|
| Description | CH7057288 is a potent and selective TRK inhibitor. |
|---|---|
| Related Catalog | |
| Target |
TRK |
| In Vitro | CH7057288 induces regression of intracranial tumors and greatly improves event-free survival in an intracranial implantation model mimicking brain metastasis. CH7057288 can be a promising therapeutic agent for TRK fusion-positive cancer. TRK receptor tyrosine kinases are expressed as fusion proteins encoded by various fusion genes across a wide variety of cancer types, including lung and colorectal cancer[1]. |
| References |
| Molecular Formula | C32H31N3O5S |
|---|---|
| Molecular Weight | 569.67 |
| Storage condition | 2-8℃ |