926018-45-3
926018-45-3 structure
| Name | HAEGTFTSD |
|---|
| Description | HAEGTFTSD is the first N-terminal 1-9 residues of GLP-1 peptide. |
|---|---|
| Related Catalog | |
| In Vitro | The GLP-1 (7-36) amide is a product of the preproglucagon gene, which is secreted from intestinal L-cells, in response to the ingestion of food. GLP-1 exerts multiple actions by stimulating insulin secretion from pancreatic β-cells, in a glucose dependent manner (insulinotropic action). GLP-1 lowers circulating plasma glucagon concentration, by inhibiting its secretion (production) from α-cells. GLP-1 also exhibits properties like stimulation of β-cell growth, appetite suppression, delays gastric emptying and stimulation of insulin sensitivity[1]. The peptide analogs of GLP-1 are useful as glucagon-like peptide 1 receptor agonists[2]. |
| References |
[1]. US20120264685 [2]. US9738697 |
| Molecular Formula | C40H57N11O17 |
|---|---|
| Molecular Weight | 963.94 |