33512-65-1

33512-65-1 structure

Name: ACTH (6-24) (human)
Chemical Name: ACTH (6-24)
CAS Number: 33512-65-1
Molecular Formula: C₁₁₁H₁₇₅N₃₅O₂₁
Molecular Weight: 2335.83
Catalog: Research Areas Cardiovascular Disease
Create Date: 2018-06-27 22:41:16
Modify Date: 2024-01-09 12:34:47
ACTH (6-24) (human) (Adrenocorticotropic hormone (6-24)) is an ACTH fragment. ACTH (6-24) (human) is a competitive inhibitor of steroidogenesis induced by ACTH (1-39) and ACTH (5-24) (Kd:13.4 and 3.4 nM). ACTH (6-24) (human) inhibits corticosterone production and cAMP accumulation induced by hPTH 1-34[1][2].

Name	ACTH (6-24)

Description	ACTH (6-24) (human) (Adrenocorticotropic hormone (6-24)) is an ACTH fragment. ACTH (6-24) (human) is a competitive inhibitor of steroidogenesis induced by ACTH (1-39) and ACTH (5-24) (Kd:13.4 and 3.4 nM). ACTH (6-24) (human) inhibits corticosterone production and cAMP accumulation induced by hPTH 1-34[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others
References	[1]. Rafferty B, et al. Corticosteroidogenesis and adenosine 3', 5'- monophosphate production by the amino-terminal (1-34) fragment of human parathyroid hormone in rat adrenocortical cells. Endocrinology. 1983 Sep;113(3):1036-42. [2]. Bristow AF, et al. Effects of ACTH (corticotropin) analogues on steroidogenesis and cyclic AMP in rat adrenocortical cells. Evidence for two different steroidogenically responsive receptors. Biochem J. 1980 Feb 15;186(2):599-603.

Molecular Formula	C₁₁₁H₁₇₅N₃₅O₂₁
Molecular Weight	2335.83