255831-16-4

255831-16-4 structure

Name: Bis-PEG3-sulfonic acid
Chemical Name: Bis-PEG3-sulfonic acid
CAS Number: 255831-16-4
Molecular Formula: C₈H₁₈O₉S₂
Molecular Weight: 322.353
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-06-23 16:18:44
Modify Date: 2025-08-26 12:10:28
Bis-PEG3-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Bis-PEG3-sulfonic acid
Synonyms	Ethanesulfonic acid, 2,2'-[oxybis(2,1-ethanediyloxy)]bis- MFCD29042373 2,2'-[Oxybis(2,1-ethanediyloxy)]diethanesulfonic acid

Description	Bis-PEG3-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562