191349-10-7

191349-10-7 structure

Name: 19,20-Epoxycytochalasin D
Chemical Name: Epoxycytochalasin D, 19,20-
CAS Number: 191349-10-7
Molecular Formula: C₃₀H₃₇NO₇
Molecular Weight: 523.617
Catalog: Research Areas Cancer
Create Date: 2019-01-21 18:39:42
Modify Date: 2024-01-09 16:28:21
19,20-Epoxycytochalasin D, a cytochalasin, is a fungal metabolite from Nemania sp. 19,20-Epoxycytochalasin D shows potent in vitro antiplasmodial activity and phytotoxicity[1].

Name	Epoxycytochalasin D, 19,20-
Synonyms	(1aR,2R,4S,6E,7aR,8S,10S,10aR,11S,13aR,14aS)-11-Benzyl-2,8-dihydroxy-2,4,10-trimethyl-9-methylene-3,13-dioxo-2,3,4,5,7a,8,9,10,10a,11,12,13,14,14a-tetradecahydro-1aH-oxireno[9,10]cycloundeca[1,2-d]isoindol-14-yl acetate 19,20-Epoxycytochalasin D 3H-Oxireno[9,10]cycloundec[1,2-d]isoindole-3,13(4H)-dione, 14-(acetyloxy)-1a,2,5,7a,8,9,10,10a,11,12,14,14a-dodecahydro-2,8-dihydroxy-2,4,10-trimethyl-9-methylene-11-(phenylmethyl)-, (1aR,2R,4S,6E,7aR,8S,10S,10aR,11S,13aR,14aS)-

Description	19,20-Epoxycytochalasin D, a cytochalasin, is a fungal metabolite from Nemania sp. 19,20-Epoxycytochalasin D shows potent in vitro antiplasmodial activity and phytotoxicity[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection
Target	Microbial Metabolite
In Vitro	19,20-Epoxycytochalasin D shows moderate toxicity to BT-549 and LLC-PK11 cell lines, with IC50 values of 7.84 µM and 8.4 µM, respectively[1].
References	[1]. Mallika Kumarihamy, et al. Antiplasmodial and Cytotoxic Cytochalasins from an Endophytic Fungus, Nemania sp. UM10M, Isolated from a Diseased Torreya taxifolia Leaf. Molecules. 2019 Feb 21;24(4):777.