1817735-39-9

1817735-39-9 structure

Name: Azido-PEG2-C2-sulfonic acid
Chemical Name: Azido-PEG2-sulfonic acid
CAS Number: 1817735-39-9
Molecular Formula: C₆H₁₃N₃O₅S
Molecular Weight: 239.249
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-07-12 01:49:20
Modify Date: 2024-01-10 16:14:14
Azido-PEG2-C2-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Azido-PEG2-sulfonic acid
Synonyms	AZIDO-PEG2-SULFONIC ACID

Description	Azido-PEG2-C2-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.