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1807539-08-7

1807539-08-7 structure
1807539-08-7 structure
  • Name: Bis-PEG4-sulfonic acid
  • Chemical Name: Bis-PEG4-sulfonic acid
  • CAS Number: 1807539-08-7
  • Molecular Formula: C10H22O10S2
  • Molecular Weight: 366.406
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-06 16:54:10
  • Modify Date: 2024-01-08 16:49:36
  • Bis-PEG4-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Bis-PEG4-sulfonic acid
Synonyms 3,6,9,12-Tetraoxatetradecane-1,14-disulfonic acid
MFCD28976669
Description Bis-PEG4-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.4±0.1 g/cm3
Molecular Formula C10H22O10S2
Molecular Weight 366.406
Exact Mass 366.065430
LogP -4.76
Index of Refraction 1.505