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1807539-04-3

1807539-04-3 structure
1807539-04-3 structure
  • Name: Fluorescein-PEG3-Amine
  • Chemical Name: Fluorescein-PEG3-Amine
  • CAS Number: 1807539-04-3
  • Molecular Formula: C29H31N3O8S
  • Molecular Weight: 581.637
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-15 21:30:47
  • Modify Date: 2024-01-10 19:28:06
  • Fluorescein-PEG3-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Fluorescein-PEG3-Amine
Synonyms Benzoic acid, 5-[(13-amino-1-thioxo-5,8,11-trioxa-2-azatridec-1-yl)amino]-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)-
5-{[(2-{2-[2-(2-Aminoethoxy)ethoxy]ethoxy}ethyl)carbamothioyl]amino}-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid
MFCD23726633
Description Fluorescein-PEG3-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.4±0.1 g/cm3
Boiling Point 827.9±75.0 °C at 760 mmHg
Molecular Formula C29H31N3O8S
Molecular Weight 581.637
Flash Point 454.5±37.1 °C
Exact Mass 581.183167
LogP 1.14
Vapour Pressure 0.0±3.2 mmHg at 25°C
Index of Refraction 1.688