1807539-01-0

1807539-01-0 structure

Name: Boc-Aminooxy-PEG4-Tos
Chemical Name: t-Boc-Aminoxy-PEG4-Tos
CAS Number: 1807539-01-0
Molecular Formula: C₂₀H₃₃NO₉S
Molecular Weight: 463.542
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-06-17 22:28:37
Modify Date: 2024-01-23 15:17:00
Boc-Aminooxy-PEG4-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	t-Boc-Aminoxy-PEG4-Tos
Synonyms	Carbamic acid, N-[2-[2-[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethoxy]ethoxy]ethoxy]-, 1,1-dimethylethyl ester MFCD28064335 2,2-Dimethyl-4-oxo-3,6,9,12,15-pentaoxa-5-azaheptadecan-17-yl 4-methylbenzenesulfonate

Description	Boc-Aminooxy-PEG4-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562