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1537170-85-6

1537170-85-6 structure
1537170-85-6 structure
  • Name: DBCO-PEG4-C2-acid
  • Chemical Name: DBCO-PEG4-Acid
  • CAS Number: 1537170-85-6
  • Molecular Formula: C30H36N2O8
  • Molecular Weight: 552.615
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-06 00:03:27
  • Modify Date: 2024-01-08 22:38:58
  • DBCO-PEG4-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name DBCO-PEG4-Acid
Synonyms 4,7,10,13-Tetraoxa-16-azaeicosan-1-oic acid, 20-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-17,20-dioxo-
ADIBO-PEG4-acid
MFCD22380749
20-(11,12-Didehydrodibenzo[b,f]azocin-5(6H)-yl)-17,20-dioxo-4,7,10,13-tetraoxa-16-azaicosan-1-oic acid
Description DBCO-PEG4-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Density 1.3±0.1 g/cm3
Boiling Point 839.7±65.0 °C at 760 mmHg
Molecular Formula C30H36N2O8
Molecular Weight 552.615
Flash Point 461.7±34.3 °C
Exact Mass 552.247192
LogP 2.08
Appearance Solid or Viscous Liquid
Vapour Pressure 0.0±3.3 mmHg at 25°C
Index of Refraction 1.597
Storage condition -20°C
RIDADR NONH for all modes of transport