1456708-45-4

1456708-45-4 structure

Name: Tos-PEG12-Tos
Chemical Name: Tos-PEG13-Tos
CAS Number: 1456708-45-4
Molecular Formula: C₃₈H₆₂O₁₇S₂
Molecular Weight: 855.019
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-11-11 11:13:36
Modify Date: 2025-08-27 18:43:23
Tos-PEG12-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Tos-PEG13-Tos
Synonyms	MFCD28334513 3,6,9,12,15,18,21,24,27,30,33-Undecaoxapentatriacontane-1,35-diyl bis(4-methylbenzenesulfonate) 3,6,9,12,15,18,21,24,27,30,33-Undecaoxapentatriacontane-1,35-diol, bis(4-methylbenzenesulfonate)

Description	Tos-PEG12-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562