1188407-46-6

1188407-46-6 structure

Name: Emtricitabine triphosphate tetrasodium salt
Chemical Name: (-)-Emtricitabine Triphosphate Tetrasodium Salt
CAS Number: 1188407-46-6
Molecular Formula: C₈H₉FN₃Na₄O₁₂P₃S
Molecular Weight:
Catalog: Signaling Pathways Anti-infection HBV
Create Date: 2018-10-18 11:42:57
Modify Date: 2024-01-31 17:17:31
Emtricitabine triphosphate tetrasodium salt is the tetrasodium salt form of Emtricitabine triphosphate (HY-131596). However，Emtricitabine triphosphate ((-)-Emtricitabine triphosphate) is the phosphorylated anabolite of Emtricitabine (HY-17427)，a nucleoside reverse transcriptase inhibitor，targeting to HIV and HBV[1].

Name	(-)-Emtricitabine Triphosphate Tetrasodium Salt

Description	Emtricitabine triphosphate tetrasodium salt is the tetrasodium salt form of Emtricitabine triphosphate (HY-131596). However，Emtricitabine triphosphate ((-)-Emtricitabine triphosphate) is the phosphorylated anabolite of Emtricitabine (HY-17427)，a nucleoside reverse transcriptase inhibitor，targeting to HIV and HBV[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection Signaling Pathways >> Anti-infection >> HBV Signaling Pathways >> Anti-infection >> Reverse Transcriptase
References	[1]. Frasca K, et al. Emtricitabine triphosphate in dried blood spots is a predictor of viral suppression in HIV infection and reflects short-term adherence to antiretroviral therapy. J Antimicrob Chemother. 2019 May 1;74(5):1395-1401. [2]. Bang LM, et al. Emtricitabine: an antiretroviral agent for HIV infection. Drugs. 2003;63(22):2413-24; discussion 2425-6.

Molecular Formula	C₈H₉FN₃Na₄O₁₂P₃S