887923-47-9

887923-47-9 structure

Name: Isogambogenic acid
Chemical Name: Isogambogenic acid
CAS Number: 887923-47-9
Molecular Formula: C₃₈H₄₆O₈
Molecular Weight: 630.767
Catalog: Research Areas Cancer
Create Date: 2018-12-28 06:28:06
Modify Date: 2025-08-27 12:31:49
Isogambogenic acid is a natural product that can be isolated from Resina Garciniae. Isogambogenic acid has cytotoxicity to cancer cell lines with IC50 values of 0.4327-5.942 μmol/L[1].

Name	Isogambogenic acid
Synonyms	(2E)-4-[(2S,13S)-7-[(2E)-3,7-Dimethyl-2,6-octadien-1-yl]-6,8-dihydroxy-17,17-dimethyl-5-(3-methyl-2-buten-1-yl)-10,14-dioxo-3,16-dioxapentacyclo[11.4.1.02,11.02,15.04,9]octadeca-4,6,8,11-tetraen -15-yl]-2-methyl-2-butenoic acid 2-Butenoic acid, 4-[(5S,12aS)-9-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-3a,4,5,7-tetrahydro-8,10-dihydroxy-3,3-dimethyl-11-(3-methyl-2-buten-1-yl)-7,13-dioxo-1,5-methano-1H,3H-furo[3,4-d]xanthen-1-yl]-2-methyl-, (2E)-

Description	Isogambogenic acid is a natural product that can be isolated from Resina Garciniae. Isogambogenic acid has cytotoxicity to cancer cell lines with IC50 values of 0.4327-5.942 μmol/L[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	Isogambogenic acid (20-68 h) 对 HL-60、SMMC-7721 和 BGC-83 细胞的 IC50 值分别为 0.1544、5.942 和 0.04327 μmol/L[1]。
References	[1]. Feng F, et al. Five novel prenylated xanthones from Resina Garciniae. J Asian Nat Prod Res. 2007 Sep-Dec;9(6-8):735-41.