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72713-23-6

72713-23-6 structure
72713-23-6 structure
  • Name: Bromo-PEG6-bromide
  • Chemical Name: Br-PEG6-bromide
  • CAS Number: 72713-23-6
  • Molecular Formula: C14H28Br2O6
  • Molecular Weight: 452.18
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-12-03 17:23:00
  • Modify Date: 2024-01-10 03:32:50
  • Bromo-PEG6-bromide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Name Br-PEG6-bromide
Synonyms MFCD30536166
Description Bromo-PEG6-bromide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs
In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].
References

[1]. Mulyana Y, et al. Oligonuclear polypyridylruthenium(II) complexes incorporating flexible polar and non-polar bridges: synthesis, DNA-binding and cytotoxicity. Dalton Trans. 2011 Feb 21;40(7):1510-23.

[2]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
Molecular Formula C14H28Br2O6
Molecular Weight 452.18

Chemsrc provides CAS#:72713-23-6 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 72713-23-6 | Chemsrc address: https://www.chemsrc.com/en/baike/1541359.html

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