1446282-38-7

1446282-38-7 structure

Name: Ald-CH2-PEG5-azide
Chemical Name: Ald-PEG5-Azide
CAS Number: 1446282-38-7
Molecular Formula: C₁₂H₂₃N₃O₆
Molecular Weight: 305.328
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2018-06-27 21:54:30
Modify Date: 2024-01-09 20:15:22
Ald-CH2-PEG5-azide is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	Ald-PEG5-Azide
Synonyms	ALD-CH2-PEG5-AZIDE

Description	Ald-CH2-PEG5-azide is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Non-cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References	[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.